Getting animated about longevity

(Jun 7, 2018)

We'll be the first to admit that what we have here doesn't exactly provide Pixar levels of entertainment.  However, with the release of v2.7.9 users of the Projections Toolkit can now generate animations of fitted past mortality curves and their extrapolation into the future.  Such animations can help analysts understand the behaviour of a forecast, as well as being a particularly useful way of communicating with non-specialists.  Below is a selection of animations from a smoothed Lee-Carter model fitted to the data for males in England & Wales between ages 50 and 104.

Figure 1 shows the logarithm of the force of mortality in the data region (1971-2015) and the forecast region.  It shows how mortality is…

Read more

Tags: survival curve, curve of deaths, mortality compression

Less is More: when weakness is a strength

(Jun 1, 2018)

A mathematical model that obtains extensive and useful results from the fewest and weakest assumptions possible is a compelling example of the art.  A survival model is a case in point.  The only material assumption we make is the existence of a hazard rate, \(\mu_{x+t}\), a function of age \(x+t\) such that the probability of death in a short time \(dt\) after age \(x+t\), denoted by \({}_{dt}q_{x+t}\), is:

\[{}_{dt}q_{x+t} = \mu_{x+t}dt + o(dt)\qquad (1)\]

(see Stephen's earlier blog on this topic).  It would be hard to think of a weaker mathematical description of mortality as an age-related process.  But from it much follows:

  • If we observe a life age \(x_i\) for a time \(t_i\), and define \(d_i = 1\) if the…

Read more

Tags: survival models, Poisson distribution

(GDP)Renewing our mail-list

(May 25, 2018)

A short and simple administrative announcement ...

In common with many other organisations, we are celebrating the arrival of the EU General Data Protection Regulation (GDPR) by renewing our mailing list. We only use our mailing list for relatively infrequent communication about our blogs, research and software. We don't sell or pass on anyone's contact details.

In order to keep things simple, we are going to start from a clean slate. So, even if you had previously joined our mailing list, in this post-GDPR world, we're going to ask for you to reconfirm your desire to hear from us. If you don't do this, you won't receive mailshots from us again (but obviously can still find out what we are up to by visiting us here).

Read more

Tags: GDPR, data protection

What's in a (file)name?

(May 14, 2018)

The upcoming EU General Data Protection Regulation places focus on the potential for personal data exposures to create a risk to the rights of natural persons. The best way to reduce such risk is to minimise the ability to identify individuals from the data you use in your analysis. Thankfully, not all data used for modelling runs the risk of identifying individuals. Group data, such as that used by Longevitas group count survival models, or the grouped death and exposure formats used within the Projections Toolkit service, are not personal data under the terms of the GDPR. Such data stands no risk of identifying individuals. However, individual data used within mortalityrating.com, and within Longevitas…

Read more

Tags: GDPR, data protection

Functions of a random variable

(May 9, 2018)

Assume we have a random variable, \(X\), with expected value \(\eta\) and variance \(\sigma^2\).  Often we find ourselves wanting to know the expected value and variance of a function of that random variable, \(f(X)\).  Fortunately there are some workable approximations involving only \(\eta\), \(\sigma^2\) and the derivatives of \(f\).  In both cases we make use of a Taylor-series expansion of \(f(X)\) around \(\eta\):

\[f(X)=\sum_{n=0}^\infty \frac{f^{(n)}(\eta)}{n!}(X-\eta)^n\]

where \(f^{(n)}\) denotes the \(n^{\rm th}\) derivative of \(f\) with respect to \(X\).  For the expected value of \(f(X)\) we then have the following second-order approximation:

\[{\rm E}[f(X)] \approx f(\eta)+\frac{f''(\eta)}{2}\sigma^2\qquad(1)\]

Read more

Tags: GLM, log link, logit link

The Karma of Kaplan-Meier

(May 7, 2018)

Our new book, Modelling Mortality with Actuarial Applications, describes several non-parametric estimators of two quantities:

  1. The survival function, \(S_x(t)\), defined as the probability that a person now aged \(x\) will survive at least \(t\) years (\({}_tp_x\) to actuaries), and
  2. The integrated hazard function, \(\Lambda_x(t) = \displaystyle\int_0^t\mu_{x+s}ds\).

The estimators of the above quantities are based on two items of data collected at the times of the observed deaths (denoted by \(t_1,t_2,\ldots,t_n\)):

  1. The number, \(d_{x+t_i}\), who died at time \(t_i\), and
  2. The number, \(l_{x+t_i^-}\), who were alive and under observation immediately before time \(t_i\) (which time we denote…

Read more

Tags: Kaplan-Meier, Nelson-Aalen, Fleming-Harrington, product integral

Battle of the Bulge

(May 1, 2018)

[Regular visitors to our blog will have guessed from the title that this posting is about obesity.  If you landed here looking for WWII material, you want the other Battle of the Bulge.]

As winter gives way to spring here in the Northern Hemisphere, many New Year's Resolutions, will have faltered.  Along with stopping smoking, losing weight is one of the more common goals, not least because the fortnight preceding the New Year is usually one of considerable excess in eating and drinking (that goes for this author, too).  However, reducing obesity and improving health is back on the agenda, as these are the specific aims of the UK's tax on sugary drinks, which was introduced in April 2018.

Losing weight (or, more accurately,…

Read more

Tags: BMI, obsesity, sugar tax

Mortalityrating and GDPR

(Apr 18, 2018)

Previously our mortalityrating.com service processed a simple file format that included postcode, gender and date of birth alongside pension amount and commencement date for individuals in an occupational pension scheme. This combination of attributes when taken together is often capable of identifying "natural persons" in the language of the upcoming EU General Data Protection Regulation (GDPR). Some might choose to mitigate risk by deleting scheme data as soon as ratings complete. However, an alternative approach would be to perform ratings without requiring a combination of attributes that may be personally identifiable. How could such a thing be acheved?

An important observation is that a postcode…

Read more

Tags: mortality, rating, GDPR, data protection

Stopping the clock on the Poisson process

(Apr 12, 2018)

"The true nature of the Poisson distribution will become apparent only in connection with the theory of stochastic processes\(\ldots\)"

Feller (1950)

 

In a previous blog, we showed how survival data lead inexorably toward a Poisson-like likelihood. This explains the common assumption that if we observe \(D_x\) deaths among \(n\) individuals, given \(E_x^c\) person-years exposed-to-risk, and we assume a constant hazard rate \(\mu\), then \(D_x\) is a Poisson random variable with parameter \(E_x^c\mu\). But then \(\Pr[D_x>n]>0\). That is, an impossible event has non-zero probability, even if it is negligibly small. What is going on?

Physicists are ever alert to the tiniest difference between…

Read more

Tags: Poisson distribution, survival model

Thymus of the essence?

(Apr 6, 2018)

We've considered cancer and its relationship to aging on a number of previous occasions. Studies published in the British Journal of Cancer in 2011 and 2018 concluded that around 40% of cases are attributable to known modifiable lifestyle and environmental factors, which is a substantial minority. Whilst risk for specific cancer subtypes will be more or less amenable to lifestyle and environment interventions than this, it is beyond doubt that the longer we live, the higher our risk of cancer becomes. But why?

A 2014 analysis of analysis of age and cancer risk proposed the view that "For most adults, age is coincidentally associated with preventable chronic conditions, avoidable exposures, and modifiable…

Read more

Tags: longevity, research, cancer, immunotherapy, immunosenescence

« Newer Posts | Older Posts »

Find by key-word


Find by date


Find by tag (show all )